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However, the expression of GPx1 has been reported to be down-regulated in thyroid cancer [44], colorectal cancer [45, 46], and gastric cancer [47], whereas GPx1 has been demonstrated to play an oncogenic role in kidney cancer [48], pancreatic cancer [49], and laryngeal squamous cell carcinoma [50]

We also noted that GSTO1 expression was higher in several colorectal cancer patient tumours as compared with normal colon tissue, consistent with our bioinformatics analysis (Supplementary Fig

10,53,54 These compounds are named according to the number of hydroxyl side-groups in the molecule

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