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This synthetic peptide falls under Category 2 of bulk substances in compounding
Preclinical studies demonstrate dose-dependent effects from 10 g/kg to 10 mg/kg administered intraperitoneally or subcutaneously in rats
The extent of preferential killing was calculated by subtracting the median gene-level shRNA score of missense mut-p53 cell lines from the median gene-level shRNA score of non-missense p53 cell lines, such that a value above 0 indicates preferential killing of missense mut-p53 cells, and a value below 0 indicates preferential killing of non-missense p53 cells