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There are four different classes of patients with LQTS: A table showing the common drugs which may cause QT prolongation Congenital long QT syndrome may be caused by an imbalance of the sympathetic innervation in the heart especially the stellate ganglion or derangements in the cardiac ion flow, resulting in prolongation of the action potential

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A delay of 6, 12, or even 24 hours has minimal impact on a drug with a six-day half-life

10.1016/j.tox.2022.153297 116 LiuZ.WangW.LiX.TangS.MengD.XiaW.et al (2022d)

It's the mechanism by which you catch these issues before they become problems