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However, injectable peptides bypass the skin barrier, and according to the American Academy of Dermatology (AAD), they may be associated with risks such as infection, allergic reactions, dosing variability, and potential systemic effects

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(2) Vukojevic J, Milavi M, Perovi D, Ili S, ili AZ, uran N, trbe S, Zorii Z, Filipi I, Brei P, Seiverth S, Sikiri P

The resultant energy crisis and diminished SOD activity increase oxidative stress, promote low-density lipoprotein (LDL) oxidation [45], and disrupt calcium homeostasis, leading to diastolic dysfunction and HF [46]

Bald, E., Sypniewski, S., Drzewoski, J