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Combining IGF-1 LR3 cycles with growth hormone secretagogues during washout periods prevents rebound suppression of endogenous GH secretion and maintains anabolic momentum during receptor recovery phases

In the context of MASLD/MASH, analogous rebound phenomena would be expected: regression of achieved steatosis resolution and potential re-emergence of inflammatory activity and fibrogenic stimuli upon drug withdrawal

doi: 10.1210/endrev/bnaa032 73 WaserBBlankAKaramitopoulouEPerrenAReubiJC

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