In vitro investigations have revealed that the ovarian steroidogenic enzymes responsible for androgen production are stimulated by oxidative stress and inhibited by antioxidants such as statins (91, 92)
Nass R, Farhy LS, Liu J, Pezzoli SS, Johnson ML, Gaylinn BD, Thorner MO
The advantages observed from this proof-of-concept trial continued 12 months after exenatide cessation [17, 86]
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However, clinical trials are still lacking to confirm these findings in humans ( Table 1 )