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In Shi et al, Lactobacillus rhamnosus GG (LGG) was shown to modulate T-bet expression and Th1 differentiation via two metabolite-mediated pathways regulation of T-bet, EPS engage the TLR2/MyD88 dendritic cell pathway with subsequent production of IL-12 and resultant STAT4 phosphorylation that directly amplifies T-bet, and SCFAs, such as butyrate, repress histone deacetylases (HDACs), enhancing Tbx21 promoter acetylation to increase T-bet expression

Stepwise multiple regression identified significant predictors, and standardized regression coefficients assessed their importance

Gut microbiota in Parkinson disease in a northern German cohort

Retrieved from Hathaway, J.T

This is more likely if you are not drinking enough water or eating a balanced diet daily