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GSTs bind the ROS substrate at its hydrophobic alpha-helical C-terminal domain, as well as reduced glutathione to its glutathione-binding site on the N-terminal domain

This is also one of the core objectives in previous clinical trials such as the observational studies on the association between riboflavin synthesis genes and type 2 diabetes using metagenomics 156 and the ongoing clinical trial with the riboflavin-overproducing strain L

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Whey fraction of milk contains whey proteins ( -lactoglobulin, -lactalbumin, Ig, bovine serum albumin, glycomacropeptide, lactoferrin and lactoperoxidase) (Reference Barone, Moloney and ORegan10) and bioactive peptides (Reference Tonolo, Folda and Cesaro11)

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