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Heart failure Heart failure is a prevalent disease that impacts nearly 2% of the global population

Biochemical assays show increased glycerol release, reflecting enhanced lipolysis, alongside reductions in intracellular lipid accumulation

Qian F, Tintle N, Jensen PN, et al

Furthermore, as a member of the TMPRSS family of serine proteases, hepsin plays crucial roles in various biological processes, including maintaining liver architecture, regulating cell growth, and influencing other serine proteases and lipid metabolism (Hsu et al

doi: 10.1073/pnas.141118798 42 SuofuYLiWJean-AlphonseFGJiaJKhattarNKLiJet al