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Instead of targeting GLP-1 and GIP, survodutide targets GLP-1 and glucagon receptors

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Most users notice subtle improvements in scalp health and texture within 48 weeks

GLP-1, however, engages the GLP-1R/ERK1/2/HDAC6 axis to modulate downstream transcriptional activity, it lowers intracellular ROS, reduces Akt and ERK1/2 phosphorylation, restores HDAC6 expression, and thereby alleviates endothelial dysfunction and excessive autophagy (Cai et al., 2018)