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Statements Author contributions MK: Data curation, Investigation, Software, Writing original draft, Writing review and editing

English search terms included: diabetic kidney disease OR diabetic nephropathy OR DKD OR DN, combined with gut microbiota OR gut microbiome OR intestinal flora OR intestinal microbiota, dietary OR nutrition OR diet OR nutritional intervention, phytochemical OR natural product OR bioactive compound OR functional food, amino acid metabolism OR metabolite OR metabolomics, gut-liver axis OR gut-kidney axis OR enterohepatic axis, short-chain fatty acids OR SCFAs, and probiotics OR prebiotics OR synbiotics. Inclusion criteria were: (1) studies addressing the associations among DKD, gut microbiota, nutritional intervention, and natural bioactive compounds

The histological analysis showed that 28 lesions (or 90%) out of the 31 were cured [242]

From preclinical evidence to human studies: what makes a drug candidate ready for a First-in-Human trial

Seek urgent medical attention for symptoms that may indicate a severe allergic reaction or another medical emergency