Gastric emptying slows substantially on tirzepatide
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Research trials highlight gastrointestinal issues like nausea or feeling full
How Tirzepatide Works Tirzepatide, on the other hand, is a dual agonistit targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors
Both are dual agonists designed to produce superior weight loss compared to single-receptor medications like semaglutide , but their different receptor combinations create distinct metabolic effects, side effect profiles, and practical considerations that matter when choosing between them