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L-cells in the upper small intestine demonstrate co-localization with gastric inhibitory peptide (GIP), and thus, bear some resemblance to neighboring K-cells, while L-cells in the lower small intestine show high levels of co-localization with PYY and CCK

It may also be an opportunity to raise awareness about the importance of performing biopsies to diagnose an often-overlooked and hard-to-treat chronic disease, said Toby Cornish, a gastrointestinal pathologist and professor at the Medical College of Wisconsin

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