Therapeutic strategies to reduce sperm DNA fragmentation typically focus on antioxidant supplementation, which aims to neutralize ROS and reduce oxidative damage to DNA
55 CONCLUSION This scoping review provides valuable insights into the complex relationship between GLP-1 agonists and psychiatric comorbidities, and further well-designed, long-term, and standardized studies are needed to clarify the mechanisms, dosage-effect relationships, and potential clinical applications of GLP-1 agonists in the field of mental health
hypoxia, other proinflammatory mediators, or cigarette smoke 49,61
For example, an acetylation defect is observed in mutant p53 3 KR , which indirectly inhibits cysteine absorption and reduces GSH consumption, leading to lipid peroxidation and ferroptosis (Jiang et al., 2015)
Choline : Essential for liver health and efficient fat transport