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Despite all the potential glamor, we must remember to use the drugs judiciously in the spirit of improving overall health.

Results In all, 39 pwIIH (mean age 33.6 years [SD 8.0], 92.3% female, median BMI 36.3 kg/m 2 [IQR 31.438.3]) were included, with 13 pwIIH being treated with GLP-1-RAs and remaining adherent to the treatment throughout the study

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Global Impact

SGLT2i have been shown to influence this process by promoting the release of Fibroblast growth factor 21, a key regulator that drives the upregulation of UCP1 and facilitates the metabolic reprogramming of adipocytes toward a thermogenic phenotype [34]