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Evinacumab for pediatric patients with homozygous familial hypercholesterolemia
The trial is currently on recruitment phase and efficacy parameters that will be measured include skin thickness (modified Rodnan Skin Score, mRSS), ACR CRISS score and disability questionnaires like HAQ-DI, among other outcomes (ClinicalTrials.gov identifier NCT04440592)
With all this in mind, it is expected that Frag 176-191 may also have depot-specific preferences on adipocytes
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