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Local subcutaneous injection near the shoulder if possible, otherwise systemic Optional TB-500: 500 to 750 mcg twice weekly for systemic support Optional GHK-Cu: 200 to 400 mcg daily, added from week three onward for collagen quality Duration: Eight to twelve weeks Critical addition: Physical therapy and progressive loading
Other strengths included allowing for appropriate time following administration of anaesthetic before biomechanical and functional testing to ensure that there was no interference between measures
Collagen I alterations occurred primarily in the vascular niche, specifically around CD31 + capillaries (Fig
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