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What is a suitable substitute for Synjardy XR 51000 (metformin extendedrelease 1000 mg plus empagliflozin 5 mg) in a type 2 diabetic patient with adequate renal function and no contraindications?

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Quick Answer: GLP-1 affects multiple brain regions including the hypothalamus, brainstem, mesolimbic reward system, hippocampus, and cortical areas involved in appetite regulation, reward processing, and cognitive function