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Adiponectin also decreases hepatic de novo glucose production and reduces free fatty acid levels in the liver (196), thereby mitigating hepatic steatosis, enhancing insulin sensitivity, and improving the circulating lipid profile ( Figure 1 Section E)

The result is systemic rather than localized

A clinical study of epithalamin demonstrated improvement in key parameters in elderly and senile patients and reduced mortality over a 15-year follow-up period

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STEP 5 Study Group