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Avoid Touching : Remind patients not to touch the treated area immediately after the procedure, as this can lead to bruising and even introduce bacteria, increasing the risk of infection

(4) Furthermore, the oxidative stress imbalance, caused by excessive ROS production, impairs the antioxidant defense system by directly damaging antioxidant enzymes (such as SOD and GPx) and depleting key antioxidant molecules like glutathione, leading to fragmentation of hyaluronic acid in the extracellular matrix and abnormal collagen cross-linking, thereby reducing the mechanical properties of cartilage (6, 22, 23)

[5] Samuels MH, Kolobova I, Smeraglio A, Niederhausen M, Janowsky JS, Schuff KG

Eur J Pharmacol (2018) 827:21526