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Although its not required in substantial amounts, vitamin B12 plays several big roles (3): Energy production Red blood cell formation (hematopoiesis) DNA synthesis Brain development Nervous system function Fatty acid synthesis Myelin formation Cardiovascular health But the thing with vitamin B12 is that although a deficiency takes a significant amount of time to develop, certain groups are more susceptible to a deficiency than others

SS-31 (elamipretine) is another compound studied for mitochondrial support

This is the minimum timeframe for meaningful change, consistent with the clinical trial data

Triggers Several potential flare-up triggers include: Stress Not getting enough sleep Medication changes Injury Excessive physical activity and/or exercise Repetitive overuse injury Smoking Spinal infections Airborne toxins can also be a trigger to a flare-up

doi: 10.1128/microbiolspec.MB-0001-2014 136 TowellA