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Endocrine 59 (2), 383394

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Seven in ten reported that they used the medications to treat a chronic condition such as heart disease or diabetes rather than to treat obesity

Additionally, per publicly available FDA and manufacturer announcements, orforglipron (Eli Lilly's Foundayo, a non-peptide oral GLP-1 receptor agonist) received FDA approval on April 1, 2026 for chronic weight management