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A 2024 study published in PNAS highlighted that both Long COVID and ME/CFS patients exhibit signs of elevated oxidative stress and aberrations in ROS clearance pathways, underscoring the role of redox imbalance in these conditions

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Hydrogen peroxide is mainly neutralized by the enzyme catalase, which turns hydrogen peroxide into water and oxygen, and the tripeptide glutathione (GSH), which converts hydrogen peroxide into water through a reducing reaction catalyzed by the enzyme glutathione peroxidase (GPX)

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Additionally, the construction of proteinprotein interaction (PPI) networks has further enhanced target screening capabilities