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The topology pattern of disulfide bridges is a very useful tool for identification protein families and superfamilies with respect to their common ancestry as well as their biological function

10.1002/med.21431 58 YanX.TangJ.dos Santos PassosC.NurissoA.Simes-PiresC

Abbreviations RBCs: Red blood cells BTT: Beta-thalassemia trait Hb: Hemoglobin PS: Peripheral smear TLC: Total leukocyte count DLC: Differential leukocyte count HPLC: High-performance liquid chromatography LDH: Lactate dehydrogenase nRBCs: Nucleated red blood cells RDW: Red cell distribution width MCV: Mean corpuscular volume MCH: Mean corpuscular hemoglobin IDA: Iron deficiency anemia MA: Megaloblastic anemia EpO: Erythropoietin EpOR: Erythropoietin receptor References Chan CW, Liu SY, Kho CS, Lau KH, Liang YS, Chu WR, Ma SK (2007) Diagnostic clues to megaloblastic anemia without macrocytosis

538 In addition to LOX, PTGS2 and ACSL4 also play important roles in phospholipid metabolism

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