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Though this trial did not report reductions in heavy alcohol drinking days (main outcome), it showed a significant attenuation of brain activation to alcohol cues

Always consult with a healthcare professional before starting any new medication or weight loss program

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In another case, detailed in the American Journal of Gastroenterology, a 60-year-old woman underwent a coffee enema and later suffered severe inflammation of the colon

Whilst there is no absolute contraindication to combining these medications, understanding their mechanisms, potential overlapping effects, and monitoring requirements is essential for safe, effective use