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Vitamin C contributes to immune defense by supporting various cellular functions of both the innate and adaptive immune system, according to a 2017 study published in Nutrients

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MOTS-C MOTS-c is a mitochondrial-derived peptide that plays a key role in regulating metabolism, energy production, and cellular stress responses

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Although the activation of POMC neurons and suppression of NPY/AgRP neurons are proposed mechanisms, the exact signaling pathways remain poorly understood and require further investigation