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Incorporating both topical and oral vitamin C can yield synergistic results in managing melasma

While it can be beneficial for liver and systemic antioxidant effects, it is a method with low targeting efficacy for improving facial pigmentation and skin tone

Additionally, JYTL can ameliorate renal function by inhibiting ROS production and modulating mitochondrial dynamics in spontaneous hypertensive rats, thereby improving mitochondrial functionality to exert renoprotective effects (Zhao et al., 2024)

Natural Vitamin E 400 IU: works synergistically with glutathione to neutralize free radicals and protect cells from oxidative stress

The most common patient population is adolescents, with 50% to 80% percent affected