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Their action involves modulation of the intestinal microbiota, production of SCFAs, and reduction of inflammation [81]

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The weight loss itself is the primary driver of health benefits, said Efferding

Specifically, each additional week of intervention was associated with an increase of 0.05 in the SMD of total GLP-1 (95% CI: 0.0002 to 0.010, p = 0.042)

Metabolic and oxidative stress have been suggested to be the cause of the resistance of CSCs to therapeutic treatment because of the metabolic plasticity induced in CSCs