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Willard, F.S., et al., Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist

Any significant calorie deficit produces lean mass loss, whether it comes from surgery, diet, or medication

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Exploring potential synergistic effects of GLP-1RAs with other established therapies, such as SGLT2 inhibitors, could unlock combination approaches for improved outcomes

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