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Some protocols use both

Each peptide targets distinct pathways: GHK-Cu modulates gene expression and copper-dependent enzymes, BPC-157 interacts with angiogenic and nitric oxide pathways, TB-500 regulates actin dynamics and cell migration, and KPV has been investigated for NF-B modulation and inflammatory cytokine signaling

Peacock, C.H

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Furthermore, Erastin-induced ferroptosis in target cells is accompanied by membrane rupture and the release of large amounts of ROS, which may further enhance autophagy via ROS-mediated activation of the AMPK/mTOR signaling pathway