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Astrocytes interact intimately with degenerating motor neurons in mouse amyotrophic lateral sclerosis (ALS)

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Diverging from liposomes composed of conventional PEG, those formed by maleimide PEG not only encompass the inherent characteristics of liposomes but also possess the unique ability of depleting GSH upon cellular entry [11]

Drug: Nitroglycerin- is typically taken sublingually (buccal cavity) where it enters the circulation and is rapidly delivered directly to the heart (without having to go through the liver first), thus avoiding the First Pass Effect