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Biological and biomimetic systems: erythrocyte membrane-coated nanoparticles and macrophage-derived exosomes exploit natural trafficking mechanisms to deliver drugs to synovial tissues, demonstrating reduced immunogenicity (Wang et al., 2025)

Managing Side Effects and Optimizing Your Experience Common side effects during the first month include nausea (30 to 40 percent of patients), constipation (25 to 35 percent), vomiting (less than 5 percent), and fatigue (15 to 20 percent)