10.4161/cbt.9.1.10392 15 BeckerK
Oxidative stress induced by HIV-1 reverse transcriptase modulates the enzymes performance in gene immunization
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Biological analyses were performed on PBMCs, assessing mitochondrial enzymology (citrate synthase and ETC complexes) and mitochondrial respiration using Seahorse XFe96 with the mitochondrial oxidative stress test
In summary, we introduced here a straightforward synthetic scheme applying activation of the Cys side chain by DSF, UV light, and Pd for chemoselective and regioselective formation of multiple disulfide bonds, tackling a decades old standing problem in peptide and protein chemistry