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No clinically meaningful changes in vital signs or in ECG (including in QTc interval) were observed in patients treated with JANUVIA

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However in the tissue of human kidney tumors, the level of cadmium is much higher in the tissue surrounding the tumor than in the tumor tissue itself, but the immuno-reactivity of (apo)-metallothionein in the latter is negligible, thus pointing at a different carcinogenic form of cadmium than that embedded in MT [177]