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But we need systemic change to make that happen. For now, patients and advocates alike are watching Congress closely, hoping that the growing scrutiny on pharmaceutical pricing will lead to real reformsand that the next time senators ask why GLP-1s are so much cheaper abroad, there will be a better answer.

Researchers measure insulin, C-peptide, and glucagon release by ELISA, and assess islet gene expression using RNA sequencing or targeted qPCR panels to characterize transcriptional responses to prolonged GLP-1R activation

Runs on 12-week prescribing cycles (closer to quarterly than monthly)

If youre thinking about the time element of it, perhaps its a little

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