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Promotes delta-wave deep sleep, regulates circadian rhythms, and enhances stress recovery through sleep architecture optimization and HPA axis modulation

However, even in large real world cohorts of patients with T1D on GLP-1RA, low rates of hypoglycemia were observed ( ADJUNCT ONE and TWO trials, the 2 largest studies with GLP-1RA in T1D, reported increased rates of hypoglycemia

GLP-1 receptor agonists demonstrate modest but clinically relevant effects on lipid profiles , though they are not primarily indicated for cholesterol management

Kariya C, Leitner H, Min E, van Heeckeren C, van Heeckeren A, Day BJ

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