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DOI: 10.1002/ajh.10321 18

Although alterations in Bax, Bcl-2, and caspase-3 expression strongly indicate activation of the intrinsic apoptotic pathway, mitochondrial integrity or membrane potential (m) was not directly assessed in this study

Research suggests a median of around 66 days of consistent repetition for a behavior to become automatic though the range is wide (18 to 254 days) depending on the behavior and the individual