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Semaglutide has proven enormously popular and sales rapidly propelled maker Novo Nordisk into the position of Europes most valuable company

Mounjaro was FDA-approved in 2022 for type 2 diabetes, while Zepbound received FDA approval in November 2023 for chronic weight management

Its FDA and EMA approvals underscore its safety and efficacy for adult patients with obesity or weight-related conditions

Semaglutide carries an alpha-aminoisobutyric acid substitution at position 8 that blocks that cleavage, plus a C18 fatty-diacid side chain that binds reversibly to circulating albumin

In a groundbreaking clinical trial known as the STEP program, researchers evaluated the efficacy of Semaglutide for weight management in individuals with obesity