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For example, a co-crystallization strategy reveals that ML162 effectively targets all catalytic tetrad residues in GPX4 by interacting with Sec46, Gln81, Trp136, and Asn137, thereby completely obstructing the active site [218]

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Cascaded strand displacement amplification and CRISPR/cas12a aptasensor utilizing moS(2) nanoflowers for colorectal cancer biomarker porphyromonas gingivalis detection