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The retatrutide versus tirzepatide comparison examines whether this triple mechanism translates to meaningfully better outcomes in clinical practice

This downregulation weakens the uptake of cystine by tumor cells, promoting lipid peroxidation and ferroptosis of tumor cells (Wang et al., 2019a)

We prepared custom diets: 2.5% Si-based agent containing AIN93M, and only AIN93M as the control (Oriental Yeast Co., Ltd., Tokyo, Japan)

However, using oral arginase inhibitors long-term to promote NO production may be challenged by the lack of isoform specificity, making it difficult to balance the roles of arginase isoforms in the urea cycle and NO production and potential disruption of nitrogen metabolism (Pudlo et al., 2017)

Our clinicians prefer to classify these medications as incretin mimetics, which include drugs that act as GLP-1s, GLP-1/GIPs, and others