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78 Augmented cAMP signaling might not only strengthen classical cAMP/PKA pathways but could also modulate cAMP/Epac-dependent pathways, including PI3K/Akt, which have been associated with aspects of cellular survival, mitochondrial bioenergetics, and autophagy in preclinical studies

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The obtained results demonstrated increased bladder preservation in cases with GLY administration in comparison with the CP group, although the effect was not as strong as in the case of Mesna + GLY administration

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