When stratified by administration route, the average percentage reductions were: Intramuscular (IM): 48.3% Sublingual: 30.7% Oral: 30.3% These results suggest that IM administration leads the most pronounced homocysteine reduction, however, sublingual and oral routes also demonstrate clinically relevant effects
A high dose of glutathione can inhibit melanin production (the pigment in skin), and in some countries glutathione injections are used (legally or not) to try to lighten the skins complexion
But like all medications and supplements, it can come with risks, particularly if you use it for a long time without instructions from your doctor
coli , and cells lacking both DsbA and endogenous glutathione can neither fully utilize the oxidative power of exogenous GSSG nor compensate the reductive power of GSH in their periplasm
There is also an increased risk of thrombotic, cardiovascular, and cerebrovascular events overall (248)
