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[1] Cell Line:Cultured Sprague-Dawley rat Achilles tendon fibroblasts (passages 2-4) Concentration:0, 0.5, 1, 2 g/mL Incubation Time:24 h Result:Did not alter total FAK, paxillin, or PCNA protein levels

This increase in lipids and intramyocellular lipid metabolites, a major inhibitor of insulin signaling and glucose transport, causes insulin resistance in muscle

PubMed, da Silva, Elaine Zayas Marcelino, et al

The significant prevalence of AITD, a long latent period and the involvement of autoimmune processes in their occurrence, development of concomitant diseases, insufficient effectiveness of the main pharmacotherapy, and a decrease in the quality of life of patients require the development of adequate approaches for the correction of immune processes in order to prevent and treat diseases

The aim of treatment is to induce remission and to maximise local effects while limiting systemic effects