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The development of cutaneous allodynia during a migraine attack clinical evidence for the sequential recruitment of spinal and supraspinal nociceptive neurons in migraine

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Historically, data on population demographics across clinical trials have not been consistently reported, particularly prior to the 2017 guidance, which requires reporting by sex/gender, race, and/or ethnicity in applicable clinical trials

(See PRECAUTIONS.) Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever the solution and container permit (see HOW SUPPLIED)

This finding further supports the safety and biocompatibility of RGD-GHK in potential applications