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Phorbol 12-myristate 13-acetate (PMA) is a well-established activator of PKC

Pre-clinical research conducted primarily in animal models informs the hypotheses for its use, but no large randomized controlled trials in humans have confirmed efficacy for any outcome - including gut-lining support, tissue-related processes, or any other claimed mechanism

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The injections are given directly into the muscle tissue, which is absorbed into the bloodstream and delivered to the liver

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