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Studies were eligible for inclusion if they were randomised controlled trials (RCTs) or observational studies that reported weight outcomes following cessation of GLP-1RA treatment in adults with overweight or obesity, defined as a BMI of 25 kg/m 2 or 23 kg/m 2 for specific populations

These factors are frequently compounded by subsequent pregnancies or further weight gain, which is why the pouch tends to be more pronounced after multiple C-sections