The biomarkers which had the effect sizes that were significant comprised of 28 biomarkers which are in descending order of the effect size given as: CTPN (SMD 37.93, p = 0.03), TG (SMD 16.60, p = 0.0007), BG (SMD 7.54, p = 0.00001), TC (SMD 7.38, p = 0.009), HDL (SMD -5.84, p= 0.0002), LDH (SMD 5.66, p = 0.0005), IL-6 (SMD 5.49, p = 0.00001), AGEs (SMD 5.43, p = 0.004), MDA (SMD 4.78, p = 0.00001), HW (SMD 4.73, p = 0.05), GSH (SMD -4.60, p = 0.009), IL-1 (SMD 4.44, p = 0.003), EF% (SMD -4.13, p = 0.00001), CC3 (SMD 3.91, p = 0.002), NLRP3 (SMD 3.59, p= 0.03), CK-MB (SMD 3.28, p = 0.004), FB% (SMD 3.25, p = 0.01), NF-KB (SMD 3.13, p = 0.0001), HMGB1 (SMD 3.00, p = 0.0001), FS% (SMD -2.91, p= 0.00001), COL III (SMD 2.43, p = 0.01), TLR4 (SMD 2.38, p = 0.009), HW/BW (SMD 2.31, p = 0.007), pJNK (SMD 1.87, p = 0.0001), BW (SMD -1.74, p= 0.05), LVIDs (SMD 1.64, p = 0.04), TGF-1 (SMD 1.50, p = 0.05), and TNF-A (SMD 1.11, p = 0.03)
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She received her bachelors degree in psychology from Ottawa University, her masters degree in clinical psychology from Phillips Graduate University and her doctorate in psychology from The Chicago School of Professional Psychology
The difference lies in which receptor-coupled signaling pathways are preferentially activated by each compounds specific binding conformation
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