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Chronic pain Another study from 1984, also published in European Neurology , examined DSIPs pain-reducing effects in seven patients with migraines, vasomotor headaches, tinnitus, and psychogenic pain attacks

The researchers attributed the inverse correlation to the tumor-suppressive effects of the autophagy induced by spermidine, which can help manage defects that commonly lead to cancer (e.g., inflammation and genomic instability).10 11 12 Cardiovascular diseases In a 2013 study, researchers determined that spermidine supplementation could potentially reverse arterial aging, which is characterized by stiffening of the arteries and dysfunction of their cellular lining.13 If you have stiff arteries, your heart has to work harder to pump blood (as seen in hypertension), which in turn elevates your risk for heart disease and stroke,14 so it's imperative to keep them as elastic as possible

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Takenoya et al