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In the complementary study from the same research group (Batistel et al., 2019), Met supply during late gestation also led to sex-dependent responses in placental metabolism and DNA methylation, improving the calf birth body weight (Batistel et al., 2019)

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The acute decrease in UMP/UDP/UTP levels that resolves despite continued TS inhibition supports the hypothesis that an increase in nucleotide salvage might be linked to our observed mitochondrial phenotypes

Cancer is caused by the replication of genetic mistakes (mutations) that go unnoticed by the cells recognition system