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That scenario plays out more often than it should, almost always due to a concentration change that wasnt communicated clearly at the time of dispensing

Back Trapp, S, Brierley, DI (29 July 2021) 'Brain GLP-1 and the regulation of food intake: GLP-1 action in the brain and its implications for GLP-1 receptor agonists in obesity treatment' British Journal of Pharmacology

Adherence: Adherence is a critical driver of value

The evidence is still early and largely from conference data rather than long-term trials, so I would not call these drugs a stone treatment

Cognitive Impairments: Users often experience memory loss, decreased ability to concentrate, and poor decision-making abilities